Even though scientific studies of the Hoodia Gordonii plant have started as early as the 1960's , it wasn’t until many years later that scientists managed to isolate a molecule that they later named P-57. The discovery of this molecule finally shed some light on how the appetite suppressing mechanism of Pure Hoodia actually works.

There is a part in our brain called the hypothalamus that is responsible for controlling the feeling of hunger and our desire to eat. When we eat, Glucose levels in the blood rise and trigger the hypothalamus into promoting a feeling of fullness. The P-57 molecule deceives the hypothalamus into thinking that one has just eaten by imitating the effect Glucose has on its. And not only that, it is well worth mentioning that the P57 molecule is many times more potent than Glucose, and so it can achieve a very long lasting sensation of fullness.